Homocysteine Levels and the Risk of Osteoporotic Fracture | Zendy

Joyce B. J. van Meurs | Zendy; R.A.M. Dhonukshe-Rutten | Zendy; Saskia M.F. Pluijm | Zendy; Marjolein van der Klift | Zendy; Róbert de Jonge | Zendy; Jan Lindemans | Zendy; C.P.G.M. de Groot | Zendy; Albert Hofman | Zendy; Jacqueline C.M. Witteman | Zendy; Johannes P.T.M. van Leeuwen | Zendy; Monique M.B. Breteler | Zendy; P. Lips | Zendy; Huibert A. P. Pols | Zendy; André G. Uitterlinden | Zendy

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Homocysteine Levels and the Risk of Osteoporotic Fracture

Author(s) -

Joyce B. J. van Meurs,

R.A.M. Dhonukshe-Rutten,

Saskia M.F. Pluijm,

Marjolein van der Klift,

Róbert de Jonge,

Jan Lindemans,

C.P.G.M. de Groot,

Albert Hofman,

Jacqueline C.M. Witteman,

Johannes P.T.M. van Leeuwen,

Monique M.B. Breteler,

P. Lips,

Huibert A. P. Pols,

André G. Uitterlinden

Publication year - 2004

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa032546

Subject(s) - medicine , homocysteine , osteoporosis , cohort , rotterdam study , quartile , prospective cohort study , body mass index , proportional hazards model , cohort study , hip fracture , population , risk factor , confidence interval , relative risk , hazard ratio , surgery , environmental health

Very high plasma homocysteine levels are characteristic of homocystinuria, a rare autosomal recessive disease accompanied by the early onset of generalized osteoporosis. We therefore hypothesized that mildly elevated homocysteine levels might be related to age-related osteoporotic fractures.

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