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Prediction of Survival in Diffuse Large-B-Cell Lymphoma Based on the Expression of Six Genes
Author(s) -
Izidore S. Lossos,
Debra K. Czerwinski,
Ash A. Alizadeh,
Mark A. Wechser,
Rob Tibshirani,
David Botstein,
Ronald Levy
Publication year - 2004
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa032520
Subject(s) - diffuse large b cell lymphoma , bcl6 , lymphoma , univariate , gene , international prognostic index , medicine , survival analysis , gene expression , microarray , multivariate analysis , computational biology , cancer research , oncology , multivariate statistics , biology , pathology , b cell , genetics , immunology , computer science , germinal center , machine learning , antibody
Several gene-expression signatures can be used to predict the prognosis in diffuse large-B-cell lymphoma, but the lack of practical tests for a genome-scale analysis has restricted the use of this method.

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