Treatment of Skin Papillomas with Topical α-Lactalbumin–Oleic Acid | Zendy

Lotta Gustafsson | Zendy; Irene Leijonhufvud | Zendy; Annika Aronsson | Zendy; AnnKristin Mossberg | Zendy; Catharina Svanborg | Zendy

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Treatment of Skin Papillomas with Topical α-Lactalbumin–Oleic Acid

Author(s) -

Lotta Gustafsson,

Irene Leijonhufvud,

Annika Aronsson,

AnnKristin Mossberg,

Catharina Svanborg

Publication year - 2004

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa032454

Subject(s) - oleic acid , lactalbumin , hamlet (protein complex) , medicine , alpha lactalbumin , dermatology , biochemistry , pharmacology , chemistry , biology , genetics

We studied the effect on skin papillomas of topical application of a complex of alpha-lactalbumin and oleic acid (often referred to as human alpha-lactalbumin made lethal to tumor cells [HAMLET]) to establish proof of the principle that alpha-lactalbumin-oleic acid kills transformed cells but not healthy, differentiated cells.

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