Open AccessImpaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
Author(s) -
Kitt Falk Petersen,
Sylvie Dufour,
Douglas E. Befroy,
Rina Garcia,
Gerald I. Shulman
Publication year - 2004
Publication title -
new england journal of medicine/the new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa031314
Subject(s) - medicine , endocrinology , insulin resistance , insulin , type 2 diabetes , lipolysis , diabetes mellitus , glucose clamp technique , adiponectin , adipose tissue , pancreatic hormone
Insulin resistance appears to be the best predictor of the development of diabetes in the children of patients with type 2 diabetes, but the mechanism responsible is unknown.