Hepatitis B e Antigen and the Risk of Hepatocellular Carcinoma
Author(s) -
HwaiI Yang,
ShengNan Lu,
YunFan Liaw,
San–Lin You,
ChienAn Sun,
LiYu Wang,
Chuhsing Kate Hsiao,
PeiJer Chen,
DingShinn Chen,
ChienJen Chen
Publication year - 2002
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa013215
Subject(s) - hbeag , hepatocellular carcinoma , hbsag , medicine , hepatitis b virus , virology , antigen , hepatitis b , immunology , virus
The presence of hepatitis B e antigen (HBeAg) in serum indicates active viral replication in hepatocytes. HBeAg is thus a surrogate marker for the presence of hepatitis B virus DNA. We conducted a prospective study to determine the relation between positivity for hepatitis B surface antigen (HBsAg) and HBeAg and the development of hepatocellular carcinoma.
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