Epidermal Growth Factor Enemas with Oral Mesalamine for Mild-to-Moderate Left-Sided Ulcerative Colitis or Proctitis | Zendy

Atul Sinha | Zendy; Jeremy M. D. Nightingale | Zendy; Kevin West | Zendy; Jorge BerlangaAcosta | Zendy; Raymond J. Playford | Zendy

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Epidermal Growth Factor Enemas with Oral Mesalamine for Mild-to-Moderate Left-Sided Ulcerative Colitis or Proctitis

Author(s) -

Atul Sinha,

Jeremy M. D. Nightingale,

Kevin West,

Jorge BerlangaAcosta,

Raymond J. Playford

Publication year - 2003

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa013136

Subject(s) - medicine , ulcerative colitis , sigmoidoscopy , gastroenterology , enema , proctitis , rectum , clinical endpoint , colitis , randomized controlled trial , inflammatory bowel disease , surgery , colonoscopy , colorectal cancer , disease , cancer

Epidermal growth factor (EGF) is a potent mitogenic peptide produced by salivary glands. We examined whether EGF enemas are an effective treatment for active left-sided ulcerative colitis and ulceration limited to the rectum (proctitis).

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