Preoperative Radiotherapy Combined with Total Mesorectal Excision for Resectable Rectal Cancer
Author(s) -
Ellen Kapiteijn,
Corrie A.M. Marijnen,
Irıs D. Nagtegaal,
Hein Putter,
Willem H. Steup,
Theo Wiggers,
H.J.T. Rutten,
Lars Påhlman,
Bengt Glimelius,
J. Han van Krieken,
J.W.H. Leer,
Cornelis J.�H. van de Velde
Publication year - 2001
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa010580
Subject(s) - medicine , total mesorectal excision , radiation therapy , colorectal cancer , surgery , randomized controlled trial , cancer
Short-term preoperative radiotherapy and total mesorectal excision have each been shown to improve local control of disease in patients with resectable rectal cancer. We conducted a multicenter, randomized trial to determine whether the addition of preoperative radiotherapy increases the benefit of total mesorectal excision.
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