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Mutagenesis in Norovirus in Response to Favipiravir Treatment
Author(s) -
Christopher Ruis,
LiAn K. Brown,
Sunando Roy,
Claire Atkinson,
Rachel Williams,
Siobhan O. Burns,
Erika Yara-Romero,
Michael Jacobs,
Richard A. Goldstein,
Judith Breuer,
David M. Lowe
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmc1806941
Subject(s) - chemistry , solubility , melting point , spectrophotometry , sulfanilamide , infrared spectroscopy , nuclear chemistry , chromatography , organic chemistry , biochemistry
Favipiravir for Chronic Norovirus Infection Norovirus may cause chronic diarrhea, especially in immunosuppressed patients. There is no established treatment. In this case report, favipiravir is shown to have some evidence of activity and to induce some selective pressure on the virus.

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