Prednisolone or Pentoxifylline for Alcoholic Hepatitis
Author(s) -
Mark J. DiNubile
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmc1506342
Subject(s) - medicine , pentoxifylline , prednisolone , alcoholic hepatitis , alcoholic liver disease , hepatitis , gastroenterology , pharmacology , cirrhosis
Copyright © 2015 Massachusetts Medical Society. BACKGROUND Alcoholic hepatitis is a clinical syndrome characterized by jaundice and liver impairment that occurs in patients with a history of heavy and prolonged alcohol use. The short-term mortality among patients with severe disease exceeds 30%. Prednisolone and pentoxifylline are both recommended for the treatment of severe alcoholic hepatitis, but uncertainty about their benefit persists.
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