Right ventricular cardiomyopathy in β-thalassaemia major | Zendy

George Hahalis | Zendy; Antonis S. Manolis | Zendy; D. Apostolopoulos | Zendy; Dimitrios Alexopoulos | Zendy; Apostolos G. Vagenakis | Zendy; Nicholas Zoumbos | Zendy

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Right ventricular cardiomyopathy in β-thalassaemia major

Author(s) -

George Hahalis,

Antonis S. Manolis,

D. Apostolopoulos,

Dimitrios Alexopoulos,

Apostolos G. Vagenakis,

Nicholas Zoumbos

Publication year - 2002

Publication title -

european heart journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.336

H-Index - 293

eISSN - 1522-9645

pISSN - 0195-668X

DOI - 10.1053/euhj.2001.2709

Subject(s) - medicine , cardiology , heart failure , pulmonary hypertension , pulmonary artery , vascular resistance , cardiac output , cardiomyopathy , hemodynamics , cardiac catheterization

To evaluate right ventricular function in patients with beta-thalassaemia major and congestive heart failure. Background In patients with beta-thalassaemia major a high incidence of cardiac involvement still exists despite improved prognosis with chelation therapy. Development of severe right heart failure is common and has been attributed to pulmonary hypertension secondary to lung haemochromatosis. However, the possibility of direct right ventricular myocardial involvement in the absence of significant pulmonary hypertension has not been adequately investigated.

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