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Mutation in the promoter region of the β-fibrinogen gene and the risk of future myocardial infarction, stroke and venous thrombosis
Author(s) -
G Blake
Publication year - 2001
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1053/euhj.2001.2692
Subject(s) - medicine , myocardial infarction , cardiology , venous thrombosis , stroke (engine) , thrombosis , fibrinogen , mutation , gene , genetics , mechanical engineering , biology , engineering
Polymorphisms in the promoter region of the beta-fibrinogen gene are associated with increased plasma fibrinogen levels. We investigated whether the distribution of the C148T polymorphism is associated with an increase in cardiovascular risk.

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