Open AccessIncidence and predictors of bleeding events after fibrinolytic therapy with fibrin-specific agents. A comparison of TNK-tPA and rt-PA
Author(s) -
Frans Van de Werf
Publication year - 2001
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1053/euhj.2001.2686
Subject(s) - medicine , fibrinolytic therapy , incidence (geometry) , fibrin , cardiology , fibrinolytic agent , fibrinolysis , tissue plasminogen activator , immunology , physics , optics
Fibrinolytic therapy increases the risk of bleeding events. TNK-tPA (tenecteplase) is a variant of rt-PA with greater fibrin specificity and reduced plasma clearance that can be given as a single bolus. We compared the incidence and predictors of bleeding events after treatment with TNK-tPA and rt-PA.
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