Effect of glycaemic control and age on low-density lipoprotein susceptibility to oxidation in diabetes mellitus type 1
Author(s) -
Ilaria Liguori,
Pasquale Abete,
John M. Hayden,
Francesco Cacciatore,
F. Rengo,
Giuseppe Ambrosio,
Domenico Bonaduce,
M Condorelli,
Peter D. Reaven,
Claudio Napoli
Publication year - 2001
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1053/euhj.2001.2655
Subject(s) - medicine , diabetes mellitus , endocrinology , vitamin e , low density lipoprotein , type 2 diabetes mellitus , lipid peroxide , type 2 diabetes , lipid oxidation , lipoprotein , lipid profile , cholesterol , antioxidant , lipid peroxidation , oxidative stress , biochemistry , chemistry
Although individuals with diabetes mellitus frequently have dyslipidaemias and high blood pressure, much of the increased risk for coronary heart disease is not explained by these and other classical risk factors. Thus, other less widely recognized risk factors, including increased susceptibility of low-density lipoprotein (LDL) to oxidation, might enhance vascular dysfunction and atherogenesis in diabetes.
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