Open AccessNorepinephrine induces action potential prolongation and early afterdepolarizations in ventricular myocytes isolated from human end-stage failing hearts
Author(s) -
M Veldkamp
Publication year - 2001
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1053/euhj.2000.2499
Subject(s) - medicine , afterdepolarization , norepinephrine , heart failure , cardiology , prolongation , myocyte , catecholamine , electrophysiology , dopamine , repolarization
Congestive heart failure is characterized by high levels of norepinephrine which is considered to be arrhythmogenic. It is unclear whether increased norepinephrine is only a marker of the severity of heart failure or whether it directly triggers ventricular arrhythmias.
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