Endogenous insulin and insulin sensitivity. An important determinant of skeletal muscle blood flow in chronic heart failure? | Zendy

Andrew R Houghton | Zendy

Open Access

Endogenous insulin and insulin sensitivity. An important determinant of skeletal muscle blood flow in chronic heart failure?

Author(s) -

Andrew R Houghton

Publication year - 1998

Publication title -

european heart journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.336

H-Index - 293

eISSN - 1522-9645

pISSN - 0195-668X

DOI - 10.1053/euhj.1997.0774

Subject(s) - medicine , insulin , endocrinology , heart failure , insulin resistance , blood flow , skeletal muscle , hemodynamics , vasodilation , forearm , cardiology , surgery

Patients with heart failure have a reduced sensitivity to insulin's actions on glucose metabolism and a compensatory increase in endogenous plasma insulin levels. As insulin has a selective vasodilatory action in skeletal muscle, we have studied the association between insulin sensitivity and central and regional haemodynamics in patients with heart failure.

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