Open AccessFast Oscillations and Epilepsy
Author(s) -
Traub Roger D.
Publication year - 2003
Publication title -
epilepsy currents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 22
eISSN - 1535-7511
pISSN - 1535-7597
DOI - 10.1046/j.1535-7597.2003.03301.x
Subject(s) - relevance (law) , neocortex , neuroscience , epilepsy , variety (cybernetics) , medicine , hippocampus , brain function , clinical significance , cognitive science , function (biology) , cognitive psychology , data science , computer science , artificial intelligence , psychology , biology , pathology , evolutionary biology , political science , law
Very fast oscillations, 80 Hz and greater (designated here VFOs or “ripples”) have been observed in the hippocampus and neocortex, under a variety of conditions that are summarized briefly later. VFOs may be of relevance for normal brain function (1–4) and could also be of relevance in the initiation of focal epileptic seizures (5,6). To determine whether such relevance indeed exists, an understanding of the cellular mechanisms of VFOs is essential. For purposes of this commentary, I shall assume that all forms of VFOs are governed by a few common basic underlying principles. Future experimental data may show that assumption to be false, but for now, the assumption at least allows the formulation of straightforward hypotheses that could stimulate experiments.