Open AccessModafinil Treatment of Opioid‐Induced Sedation
Author(s) -
Webster Lynn,
Andrews Megan,
Stoddard Gregory
Publication year - 2003
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1046/j.1526-4637.2003.03014.x
Subject(s) - modafinil , sedation , medicine , anesthesia , opioid , epworth sleepiness scale , psychiatry , polysomnography , receptor , apnea
Study Objective. The purpose of this study was to assess the efficacy of modafinil in combating opioid‐induced sedation. Design. A 1‐year retrospective chart review of all patients receiving modafinil, a wake‐promoting agent, to treat opioid‐induced sedation. Opioid‐induced sedation was measured using Epworth Sleepiness Scale (ESS). Setting. Outpatient, private practice. Patients. Eleven adult patients, six female and five male, being treated with opioids for chronic, nonmalignant pain. Results. A significant decrease was observed between pretreatment and posttreatment ESS measurements during modafinil treatment. Conclusion. The results suggest an improvement in opioid‐induced sedation in patients treated for nonmalignant pain.