Open AccessRecurrence and survival after resection of adenocarcinoma of the gastric cardia
Author(s) -
Stassen L. P. S.,
Bosman F. T.,
Siersema P. D.,
Hop W. C. J.,
Blomjous J. G. A. M.,
Tilanus H. W.
Publication year - 2000
Publication title -
diseases of the esophagus
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.115
H-Index - 63
eISSN - 1442-2050
pISSN - 1120-8694
DOI - 10.1046/j.1442-2050.2000.00070.x
Subject(s) - medicine , multivariate analysis , lymph node , adenocarcinoma , dissection (medical) , retrospective cohort study , gastric cardia , surgery , survival rate , carcinoma , neoadjuvant therapy , gastric adenocarcinoma , survival analysis , lymph , cancer , pathology , breast cancer
In a retrospective study, the results after resection of carcinoma of the gastric cardia in the era without neoadjuvant therapy or extended lymph node dissection were evaluated. All 184 patients who underwent resection between January 1983 and December 1993 were included. Recurrence of disease, survival and prognostic factors were determined. The overall cumulative 5‐year recurrence rate was 71% and the survival rate 23%. Multivariate analysis identified locoregional lymph node and distant metastases as the crucial prognosticators of recurrence of disease and survival. These results were similar to those from a previous study concerning our patients operated during the years 1983–88. The prognosis of a resected cardiacarcinoma has remained unchanged in our hands over the past 10 years. These results stress the importance of exploring new ways, such as the use of new diagnostic tools, to optimize preoperative patient selection and more aggressive treatment regimens to improve final outcome.