Open Access(TTAGGG) n telomeric sequence in selachian chromosomes
Author(s) -
Rocco Lucia,
Costagliola Domenico,
Stingo Vincenzo
Publication year - 2001
Publication title -
heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.441
H-Index - 118
eISSN - 1365-2540
pISSN - 0018-067X
DOI - 10.1046/j.1365-2540.2001.00945.x
Subject(s) - biology , telomere , karyotype , metaphase , fluorescence in situ hybridization , chromosome , fish <actinopterygii> , sequence (biology) , genome , genetics , centromere , repeated sequence , dna , evolutionary biology , gene , fishery
The distribution of telomeric sequence (TTAGGG) n in the genomes of Chondrichthian species at different stages of evolution was investigated both by DNA genomic hybridization, and by fluorescence in‐situ hybridization (FISH) of metaphase chromosomes. The sequence is highly conserved in all the species examined. FISH revealed a label uptake only by the telomeres in Raja asterias . However, in Torpedo ocellata , we revealed pericentromeric and interstitial sequence localization on some chromosome pairs in addition to the hybridization signal on telomeres. These findings confirm that the karyotype evolution of these fish began by Robertsonian fusion.