Open AccessLong‐term results of treating hepatic colorectal metastases with cryosurgery
Author(s) -
Ruers T. J. M.,
Joosten J.,
Jager G. J.,
Wobbes T.
Publication year - 2001
Publication title -
british journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.202
H-Index - 201
eISSN - 1365-2168
pISSN - 0007-1323
DOI - 10.1046/j.1365-2168.2001.01766.x
Subject(s) - medicine , cryosurgery , surgery , resection , survival rate , colorectal cancer , overall survival , cancer
Background: The purpose of this study was to determine the long‐term efficacy of cryosurgery as an adjunct to hepatic resection in patients with colorectal liver metastases not amenable to resection alone. Methods: Thirty patients met the following inclusion criteria: metastases confined to the liver and judged irresectable, ten or fewer metastases, cryosurgery alone or in combination with hepatic resection allowed tumour clearance. Results: Median follow‐up was 26 (range 9–73) months. Overall 1‐ and 2‐year survival rates were 76 and 61 per cent respectively. Median survival was 32 months. Disease‐free survival at 1 year was 35 per cent, at 2 years 7 per cent. Six patients developed recurrence at the site of cryosurgery; given that the total number of cryosurgery‐treated lesions was 69 the local recurrence rate was 9 per cent. Conclusion: In patients with colorectal liver metastases, local ablative techniques can be used as an effective adjunct to hepatic resection to obtain tumour clearance. © 2001 British Journal of Surgery Society Ltd