Non-coding RNA in cancer | Zendy

Huiwen Yan | Zendy; Pengcheng Bu | Zendy

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Non-coding RNA in cancer

Author(s) -

Huiwen Yan,

Pengcheng Bu

Publication year - 2021

Publication title -

essays in biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.351

H-Index - 66

eISSN - 1744-1358

pISSN - 0071-1365

DOI - 10.1042/ebc20200032

Subject(s) - non coding rna , microrna , rna , biology , piwi interacting rna , computational biology , encode , long non coding rna , circular rna , genome , small nucleolar rna , genetics , mechanism (biology) , function (biology) , gene , rna interference , philosophy , epistemology

Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, in this review, we mainly focus on the recent studies of the function, regulatory mechanism and therapeutic potential of the ncRNAs including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA) and PIWI interacting RNA (piRNA), in different type of cancers.

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