Pathogenic role of human C-reactive protein in diabetic retinopathy
Author(s) -
Fangfang Qiu,
Xiang Ma,
Younghwa Shin,
Jianglei Chen,
Qian Chen,
Kelu Zhou,
Wenjing Wu,
Wentao Liang,
Yalin Wu,
Qing Song,
Jianxing Ma
Publication year - 2020
Publication title -
clinical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.91
H-Index - 138
eISSN - 1470-8736
pISSN - 0143-5221
DOI - 10.1042/cs20200085
Subject(s) - diabetic retinopathy , retinal , medicine , nitrotyrosine , retina , diabetes mellitus , reactive oxygen species , streptozotocin , oxidative stress , apoptosis , electroretinography , erg , endocrinology , ophthalmology , microbiology and biotechnology , chemistry , biology , nitric oxide , biochemistry , nitric oxide synthase , neuroscience
Elevated blood levels of C-reactive protein (CRP) are associated with both type 1 and type 2 diabetes and diabetic complications, such as diabetic retinopathy (DR). However, its pathogenic role in DR remains unknown. The present study aims to investigate the potential role of CRP in DR pathogenesis and explore its underlying mechanism.
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