Open AccessHow RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes
Author(s) -
David M.J. Lilley
Publication year - 2017
Publication title -
biochemical society transactions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.562
H-Index - 144
eISSN - 1470-8752
pISSN - 0300-5127
DOI - 10.1042/bst20160158
Subject(s) - ribozyme , ligase ribozyme , computational biology , nuclease , rna , biology , chemistry , genetics , biochemistry , enzyme , gene
Recent structural and mechanistic studies have shed considerable light on the catalytic mechanisms of nucleolytic ribozymes. The discovery of several new ribozymes in this class has now allowed comparisons to be made, and the beginnings of mechanistic groupings to emerge.
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