Identification of PSMD7 as a prognostic factor correlated with immune infiltration in head and neck squamous cell carcinoma | Zendy

Si Zhang | Zendy; Siwei Yu | Zendy; Jiulong Wang | Zendy; Zhigang Cheng | Zendy

Open Access

Identification of PSMD7 as a prognostic factor correlated with immune infiltration in head and neck squamous cell carcinoma

Author(s) -

Si Zhang,

Siwei Yu,

Jiulong Wang,

Zhigang Cheng

Publication year - 2021

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20203829

Subject(s) - head and neck squamous cell carcinoma , immune system , cancer research , human protein atlas , oncology , medicine , infiltration (hvac) , head and neck cancer , biology , gene , immunology , radiation therapy , protein expression , biochemistry , physics , thermodynamics

Recurrent locally advanced or metastatic head and neck squamous cell carcinoma (HNSCC) is associated with dismal prognosis because of its highly invasive behavior and resistance to conventional intensive chemotherapy. The identification of effective markers for early diagnosis and prognosis is important for reducing mortality and ensuring that therapy for HNSCC is effective. Proteasome 26S subunit, non-ATPase 7 (PSMD7) is an ATP-independent component of the 19S regulatory subunit. The prognostic value of PSMD7 and the association with immune infiltration in HNSCC remains unclear.

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