Network pharmacology for the identification of phytochemicals in traditional Chinese medicine for COVID-19 that may regulate interleukin-6 | Zendy

Wenhao Niu | Zendy; Feng Wu | Zendy; Wenyue Cao | Zendy; Zonggui Wu | Zendy; Yu-Chieh Chao | Zendy; Fei Peng | Zendy; Chun Liang | Zendy

Open Access

Network pharmacology for the identification of phytochemicals in traditional Chinese medicine for COVID-19 that may regulate interleukin-6

Author(s) -

Wenhao Niu,

Feng Wu,

Wenyue Cao,

Zonggui Wu,

Yu-Chieh Chao,

Fei Peng,

Chun Liang

Publication year - 2020

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20202583

Subject(s) - identification (biology) , covid-19 , traditional medicine , medicine , pharmacology , traditional chinese medicine , computational biology , interleukin , biology , immunology , virology , cytokine , alternative medicine , disease , infectious disease (medical specialty) , pathology , botany , outbreak

´Three formulas and three medicines,' namely, Jinhua Qinggan Granule, Lianhua Qingwen Capsule, Xuebijing Injection, Qingfei Paidu Decoction, HuaShi BaiDu Formula, and XuanFei BaiDu Granule, were proven to be effective for coronavirus disease 2019 (COVID-19) treatment. The present study aimed to identify the active chemical constituents of this traditional Chinese medicine (TCM) and investigate their mechanisms through interleukin-6 (IL-6) integrating network pharmacological approaches.

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