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Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer
Author(s) -
Yali Wang,
Kun Zheng,
Xiuqiong Chen,
Rui Chen,
Yanmei Zou
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20202564
Subject(s) - immunotherapy , kegg , biology , cancer , gene , immune system , computational biology , bioinformatics , cancer immunotherapy , oncology , cancer research , immunology , gene expression , medicine , genetics , transcriptome
The present study aimed to use bioinformatics tools to explore pivotal genes associated with the occurrence of gastric cancer (GC) and assess their prognostic significance, and link with clinicopathological parameters. We also investigated the predictive role of COL1A1, THBS2, and SPP1 in immunotherapy.

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