High expression of LEF1 correlates with poor prognosis in solid tumors, but not blood tumors: a meta-analysis | Zendy

Xiaoqi Yang | Zendy; Haoran Liu | Zendy; Tao Ye | Zendy; Zhangqun Ye | Zendy

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High expression of LEF1 correlates with poor prognosis in solid tumors, but not blood tumors: a meta-analysis

Author(s) -

Xiaoqi Yang,

Haoran Liu,

Tao Ye,

Zhangqun Ye

Publication year - 2020

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20202520

Subject(s) - meta analysis , hazard ratio , medicine , oncology , biomarker , confidence interval , cancer , biology , biochemistry

Previously published studies have indicated that lymphoid enhancer-binding factor 1 (LEF1) expression could be recognized as a valuable biomarker to evaluate clinical outcome for various types of malignant cancer, but the results remained controversial. Therefore, we conducted this meta-analysis to pool the published estimates and discuss the relationship of LEF1 expression with cancer prognosis.

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