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LncRNA H19 regulates smooth muscle cell functions and participates in the development of aortic dissection through sponging miR-193b-3p
Author(s) -
Mingming Ren,
Tao Wang,
Xiaolong Wei,
Yizeng Wang,
Chun Ouyang,
Yilian Xie,
Xiaoqiang Ye,
Zhen Han
Publication year - 2021
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20202298
Subject(s) - smooth muscle , dissection (medical) , cell , aortic dissection , microbiology and biotechnology , cancer research , biology , medicine , anatomy , aorta , genetics
Multiple studies showed that long-chain noncoding RNA H19 (LncRNA H19) is high-expressed in human and mouse abdominal aortic aneurysms (AAAs). We speculated that it plays an important role in arterial disease, and therefore studied the role and mechanism of H19 in aortic dissection (AD).

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