Computational analysis and verification of molecular genetic targets for glioblastoma
Author(s) -
Xue Liang,
Haibing Liu,
Yehuang Chen,
Liangfeng Wei,
Jingfang Hong
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20201401
Subject(s) - kegg , gene , neuropilin 1 , biology , cancer research , metacestode , axon guidance , computational biology , bioinformatics , gene expression , genetics , receptor , immunology , gene ontology , cestoda , helminths , vascular endothelial growth factor , vegf receptors
Glioblastoma (GBM) is the most common malignant brain tumor with a poor prognosis. The initial treatment for high-grade gliomas is surgical excision. However, even with concomitant use of radiation or chemotherapy, patients are still prone to recurrence. The specific pathogenesis of GBM is still controversial.
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