Open AccessCotinine inhibits TLR4/NF-κB signaling pathway and improves deep vein thrombosis in rats
Author(s) -
Zhiyuan Cheng,
Wei Jia,
Xuan Tian,
Peng Jiang,
Yunxin Zhang,
Jinyong Li,
Chenyang Tian,
Jianlong Liu
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20201293
Subject(s) - deep vein , thrombosis , tlr4 , signal transduction , chemistry , nf κb , microbiology and biotechnology , medicine , biology , biochemistry
The present study was designed to explore the regulatory mechanisms and influences of cotinine on deep vein thrombosis (DVT) in rats via the toll-like receptor 4/nuclear factor κ binding (TLR-4/NF-κB) pathway.
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