miR-29b-3p inhibits post-infarct cardiac fibrosis by targeting FOS | Zendy

Yongliang Xue | Zendy; Fan Xue-fang | Zendy; Ruobing Yang | Zendy; Yuanyuan Jiao | Zendy; Yang Li | Zendy

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miR-29b-3p inhibits post-infarct cardiac fibrosis by targeting FOS

Author(s) -

Yongliang Xue,

Fan Xue-fang,

Ruobing Yang,

Yuanyuan Jiao,

Yang Li

Publication year - 2020

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20201227

Subject(s) - cardiac fibrosis , western blot , fibrosis , microrna , myocardial fibrosis , mmp2 , cell growth , medicine , myocardial infarction , transforming growth factor , cancer research , mmp9 , biology , downregulation and upregulation , gene , biochemistry , cancer , metastasis

Cardiac fibrosis after myocardial infarction (MI) is a major cause of heart deterioration. Recently, the roles of microRNAs (miRNAs) in various cardiovascular diseases associated with cardiac fibrosis have been extensively investigated. The present study aimed to investigate the role and mechanism of miR-29b-3p in cardiac fibrosis after MI.

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