Association between vitamin D receptor BsmI, FokI, and Cdx2 polymorphisms and osteoporosis risk: an updated meta-analysis | Zendy

Bin Chen | Zendy; Wang-fa Zhu | Zendy; Yi-Yang Mu | Zendy; Biao Liu | Zendy; Hongzhuo Li | Zendy; XiaoFeng He | Zendy

Open Access

Association between vitamin D receptor BsmI, FokI, and Cdx2 polymorphisms and osteoporosis risk: an updated meta-analysis

Author(s) -

Bin Chen,

Wang-fa Zhu,

Yi-Yang Mu,

Biao Liu,

Hongzhuo Li,

XiaoFeng He

Publication year - 2020

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20201200

Subject(s) - foki , calcitriol receptor , meta analysis , medicine , osteoporosis , vitamin d and neurology , odds ratio , oncology , endocrinology , polymorphism (computer science) , allele , genetics , biology , gene

Many studies have reported the association between vitamin D receptor (VDR) polymorphism and osteoporosis risk. However, their results were conflicting. Six previous meta-analyses have been published to analyze VDR BsmI, FokI, and Cdx2 polymorphisms on osteoporosis risk. However, they did not evaluate the reliability of statistically significant associations. Furthermore, a lot of new articles have been published on these themes, and therefore an updated meta-analysis was performed to further explore these issues.

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