β-glucan from Lentinus edodes inhibits breast cancer progression via the Nur77/HIF-1α axis | Zendy

Xiuru Zhang | Zendy; Tingting Li | Zendy; Shuwen Liu | Zendy; Yiming Xu | Zendy; Minjun Meng | Zendy; Xiu-Min Li | Zendy; Zhichao Lin | Zendy; Qici Wu | Zendy; Yu Xue | Zendy; Yutian Pan | Zendy; Gulimiran Alitongbieke | Zendy

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β-glucan from Lentinus edodes inhibits breast cancer progression via the Nur77/HIF-1α axis

Author(s) -

Xiuru Zhang,

Tingting Li,

Shuwen Liu,

Yiming Xu,

Minjun Meng,

Xiu-Min Li,

Zhichao Lin,

Qici Wu,

Yu Xue,

Yutian Pan,

Gulimiran Alitongbieke

Publication year - 2020

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20201006

Subject(s) - cancer research , mg132 , biology , metastasis , breast cancer , cancer , proteasome inhibitor , proteasome , microbiology and biotechnology , genetics

β-glucan from Lentinus edodes (LNT) is a plant-derived medicinal fungus possessing significant bioactivities on anti-tumor. Both hypoxia-induced factor-1α (HIF)-1α and Nur77 have been shown to be involved in the development of breast cancer. However, there is yet no proof of Nur77/HIF-1α involvement in the process of LNT-mediated tumor-inhibition effect.

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