Lack of association between IGF2BP2 rs4402960 polymorphism and gestational diabetes mellitus: a case–control study, meta-analysis and trial sequential analysis | Zendy

Jing Liu | Zendy; Guang Song | Zendy; Ge Zhao | Zendy; Tao Meng | Zendy

Open Access

Lack of association between IGF2BP2 rs4402960 polymorphism and gestational diabetes mellitus: a case–control study, meta-analysis and trial sequential analysis

Author(s) -

Jing Liu,

Guang Song,

Ge Zhao,

Tao Meng

Publication year - 2020

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20200990

Subject(s) - meta analysis , medicine , odds ratio , genetic model , gestational diabetes , subgroup analysis , confidence interval , genotype , biology , genetics , pregnancy , gestation , gene

It is well known that insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) rs4402960 polymorphism is associated with Type 2 diabetes mellitus, which has a shared genetic background with gestational diabetes mellitus (GDM). Previous studies have yielded controversial results about the link between IGF2BP2 rs4402960 polymorphism and GDM risk. Thus, a meta-analysis was performed to obtain more conclusive results.

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