Evaluation of epithelial progenitor cells and growth factors in a preclinical model of wound healing induced by mesenchymal stromal cells
Author(s) -
Giselle Ramos-González,
Olga Wittig,
Dylana DiazSolano,
Lianeth Salazar,
Carlos A. AyalaGrosso,
José E. Cardier
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20200461
Subject(s) - wound healing , mesenchymal stem cell , keratinocyte growth factor , progenitor cell , cd34 , stromal cell , basic fibroblast growth factor , transplantation , medicine , fibroblast , cancer research , growth factor , pathology , stem cell , immunology , biology , microbiology and biotechnology , cell culture , surgery , receptor , genetics
Skin wounds continue to be a global health problem. Several cellular therapy protocols have been used to improve and accelerate skin wound healing. Here, we evaluated the effect of transplantation of mesenchymal stromal cells (MSC) on the wound re-epithelialization process and its possible relationship with the presence of epithelial progenitor cells (EPC) and the expression of growth factors.
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