Relationship between MEG3 gene polymorphism and risk of gastric cancer in Chinese population with high incidence of gastric cancer
Author(s) -
Xiaoling Kong,
Sheng Yang,
Caiping Liu,
Hanqing Tang,
Yingan Chen,
Xiaomei Zhang,
Yun Zhou,
Geyu Liang
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20200305
Subject(s) - odds ratio , medicine , cancer , confidence interval , single nucleotide polymorphism , oncology , population , gastroenterology , genotype , genetics , biology , gene , environmental health
Gastric cancer is the most common gastrointestinal malignancy in China and results from a combination of genetic and environmental factors. The present study was conducted to investigate the relationship between long noncoding RNA (lncRNA) materally expressed gene 3 (MEG3) single nucleotide polymorphisms (SNPs) and the risk of gastric cancer and to construct a genetic-environmental risk assessment model.
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