Open AccessDipeptidyl peptidase like 6 promoter methylation is a potential prognostic biomarker for pancreatic ductal adenocarcinoma
Author(s) -
Xin Zhao,
Di Cao,
Zhangyong Ren,
Zhe Liu,
Shaocheng Lv,
Ji-Qiao Zhu,
Lixin Li,
Ren Lang,
Qiang He
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20200214
Subject(s) - methylation , dna methylation , promoter , cancer research , biology , carcinogenesis , trichostatin a , microbiology and biotechnology , oncology , medicine , cancer , gene , gene expression , histone , genetics , histone deacetylase
Hypermethylation of gene promoters plays an important role in tumorigenesis. The present study aimed to identify and validate promoter methylation-driven genes (PMDGs) for pancreatic ductal adenocarcinoma (PDAC).
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