Foam cells promote atherosclerosis progression by releasing CXCL12
Author(s) -
Lingxing Li,
Zhenlan Du,
Bing Rong,
Dapeng Zhao,
Aiping Wang,
Yuzhen Xu,
Huanyi Zhang,
Xue Bai,
Jingquan Zhong
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20193267
Subject(s) - oil red o , vascular smooth muscle , chemokine , staining , in vitro , in vivo , cell growth , h&e stain , inflammation , mtt assay , cell , immunohistochemistry , chemistry , ex vivo , microbiology and biotechnology , biology , medicine , pathology , immunology , endocrinology , biochemistry , smooth muscle , adipogenesis
Atherosclerosis (AS) is a chronic inflammatory disease that contributes to multiple cardiovascular diseases (CVDs), and foam cell formation plays important roles in the progression of AS. There is an urgent need to identify new molecular targets for treating AS, and thereby improve the quality of life and reduce the financial burden of individuals with CVD.
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