Open AccessMicroRNA-101-3p inhibits fibroblast-like synoviocyte proliferation and inflammation in rheumatoid arthritis by targeting PTGS2
Author(s) -
Qiaofeng Wei,
Fang Lv,
Hongju Zhang,
Xinfang Wang,
Geng Qin,
Xiuying Zhang,
Tongying Li,
Shujun Wang,
Yajuan Wang,
Yanhui Cui
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20191136
Subject(s) - rheumatoid arthritis , apoptosis , inflammation , fibroblast , microrna , arthritis , tumor necrosis factor alpha , western blot , cancer research , medicine , immunology , chemistry , in vitro , biochemistry , gene
Rheumatoid arthritis (RA) is the most frequently occurring inflammatory arthritis. The present study was performed to characterize the role of microRNA-101-3p (miR-101-3p) and prostaglandin-endoperoxide synthase 2 (PTGS2) in inflammation and biological activities of fibroblast-like synoviocytes (FLSs) in RA.
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