Open AccessProstaglandin E1 protects cardiomyocytes against hypoxia-reperfusion induced injury via the miR-21-5p/FASLG axis
Author(s) -
Mingxiang Tang,
Hongwei Pan,
Zhaofen Zheng,
Yin Guo,
Jianqiang Peng,
Jun Yang,
Yangping Luo,
Jin He,
Sulan Yan,
Peng Wang,
Yi Zhang,
Yulu Zhou
Publication year - 2019
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20190597
Subject(s) - hypoxia (environmental) , prostaglandin , reperfusion injury , chemistry , prostaglandin e , microbiology and biotechnology , pharmacology , medicine , biology , ischemia , oxygen , organic chemistry
Prostaglandin-E1 (PGE1) is a potent vasodilator with anti-inflammatory and antiplatelet effects. However, the mechanism by which PGE1 contributes to the amelioration of cardiac injury remains unclear.
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