Investigation of the association between obesity and insulin-induced gene 1 polymorphism at 7q36.3 region in Uygur population in Xinjiang, China
Author(s) -
Jing Tao,
Mayila Abudoukelimu,
Xin Shen,
Jun Liu,
Fengxia Wang,
Jie Yuan,
Pei-Pei Gu,
Wei Zhu,
Xiaotian Zhang,
Zhao Wang,
Yi-Tong Ma,
Guoqing Li
Publication year - 2019
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20190498
Subject(s) - genotype , single nucleotide polymorphism , obesity , medicine , allele , polymorphism (computer science) , snp , biology , endocrinology , genotyping , confounding , genetics , gene
Obesity is a common heritable trait and a major risk factors of chronic and metabolic diseases. Insulin-induced gene 1 (INSIG1) is known to play important roles in cholesterol and triacylglycerol (TAG) metabolism. In the present study, our primary objective was to explore whether the single nucleotide polymorphisms (SNPs) in INSIG1 gene were associated with obesity in Uygur subjects, in Xinjiang, China.
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