Open AccessThe multidrug resistance can be reversed for the decrease of P-gp and LRP by inhibiting PI3K/Akt/NF-κB signal pathway in nasopharynx carcinoma
Author(s) -
Jin Liu,
Ming-Yi Zhu,
Yun Feng,
Qian-Li Tang,
Meng Xu
Publication year - 2020
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20190239
Subject(s) - pi3k/akt/mtor pathway , protein kinase b , multiple drug resistance , cancer research , chemistry , signal transduction , biology , drug resistance , biochemistry , genetics
To investigate the relationship between PI3K/Akt/NF-κB cellular signal pathway and the expression of P-gp and LRP in multidrug resistance (MDR) cell of nasopharyngeal carcinoma.
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