Function analysis of differentially expressed microRNAs in TGF-β1-induced cardiac fibroblasts differentiation | Zendy

Suxuan Liu | Zendy; Wen Ke | Zendy; Yang Liu | Zendy; Zhenzhen Zhao | Zendy; Lina An | Zendy; Xiaohua You | Zendy; Fan Yang | Zendy; Xiangqun Yang | Zendy; Guokun Wang | Zendy; Xianxian Zhao | Zendy

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Function analysis of differentially expressed microRNAs in TGF-β1-induced cardiac fibroblasts differentiation

Author(s) -

Suxuan Liu,

Wen Ke,

Yang Liu,

Zhenzhen Zhao,

Lina An,

Xiaohua You,

Fan Yang,

Xiangqun Yang,

Guokun Wang,

Xianxian Zhao

Publication year - 2019

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20182048

Subject(s) - microrna , transforming growth factor , function (biology) , microbiology and biotechnology , cardiac function curve , cellular differentiation , biology , chemistry , computational biology , genetics , medicine , gene , heart failure

Cardiac fibroblasts differentiation plays a critical role in cardiac remodeling and failure, but the underlying molecular mechanisms are still poorly understood. MicroRNAs (miRNAs) had been identified as important regulators during cell differentiation. The aim of the present study was to screen the miRNAs involved in regulation of cardiac fibroblasts differentiation.

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