Phospholipases D: making sense of redundancy and duplication | Zendy

Andrew J. Morris | Zendy

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Phospholipases D: making sense of redundancy and duplication

Author(s) -

Andrew J. Morris

Publication year - 2019

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20181883

Subject(s) - gene , biology , organism , gene duplication , redundancy (engineering) , evolutionary biology , government (linguistics) , genetics , computational biology , computer science , philosophy , linguistics , operating system

Why have two genes when one would suffice? Evolutionary pressure means that biology, unlike government, is generally intolerant of wasted effort. Therefore, when multiple genes exist presumably they are there to provide some benefit to the organism even if that benefit is not immediately obvious to us scientists. A recent report from Raghu and colleagues ( Biosci. Rep. (2018) 38 , pii: BSR20181690) [ 1 ] sheds some light on one possible reason for the existence of two Phospholipases D genes in chordates when only one is present in invertebrates.

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