Association of FcεRIβ polymorphisms with risk of asthma and allergic rhinitis: evidence based on 29 case–control studies | Zendy

Huanhuan Guo | Zendy; Tao Peng | Zendy; Ping Luo | Zendy; Huabin Li | Zendy; Shuo Huang | Zendy; Shuang Li | Zendy; Weidong Zhao | Zendy; Xuhong Zhou | Zendy

Open Access

Association of FcεRIβ polymorphisms with risk of asthma and allergic rhinitis: evidence based on 29 case–control studies

Author(s) -

Huanhuan Guo,

Tao Peng,

Ping Luo,

Huabin Li,

Shuo Huang,

Shuang Li,

Weidong Zhao,

Xuhong Zhou

Publication year - 2018

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20180177

Subject(s) - meta analysis , single nucleotide polymorphism , asthma , confidence interval , medicine , case control study , odds ratio , immunoglobulin e , genetic model , immunology , genotype , genetics , biology , gene , antibody

Accumulating evidence has shown that allergic diseases are caused by a complex interaction of genetic and environmental factors, some single nucleotide polymorphisms (SNPs) existing in high-affinity IgE receptor β chain (FcεRIβ) are potential risk factors for allergic diseases. However, the results have been inconsistent and inconclusive due to the limited statistical power in individual study. Thus, we conducted a meta-analysis to systematically evaluate the association between FcεRIβ SNPs and allergic diseases risk.

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