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Yeast mitochondrial HMG proteins: DNA-binding properties of the most evolutionarily divergent component of mitochondrial nucleoids
Author(s) -
Jana Bakkaiova,
Victoria Marini,
Smaranda Willcox,
Jozef Nosek,
Jack D. Griffith,
Lumír Krejčí,
Ľubomír Tomáška
Publication year - 2015
Publication title -
bioscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 77
eISSN - 1573-4935
pISSN - 0144-8463
DOI - 10.1042/bsr20150275
Subject(s) - nucleoid , biology , yarrowia , yeast , mitochondrial dna , saccharomyces cerevisiae , schizosaccharomyces pombe , helicase , biochemistry , dna , nucleoprotein , genetics , dna binding protein , microbiology and biotechnology , gene , rna , transcription factor , escherichia coli
Comparative biochemical analysis of mtHMG proteins from distantly related yeast species revealed that they exhibit a preference for recombination/replication intermediates. We discuss how these biochemical characteristics relate to the role of mtHMG proteins in mtDNA compaction and evolution.

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