Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria | Zendy

Subir Roy Chowdhury | Zendy; Jelena Djordjevic | Zendy; Benedict C. Albensi | Zendy; Paul Fernyhough | Zendy

Open Access

Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria

Author(s) -

Subir Roy Chowdhury,

Jelena Djordjevic,

Benedict C. Albensi,

Paul Fernyhough

Publication year - 2015

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20150244

Subject(s) - safranin , mitochondrion , respiration , bioenergetics , cellular respiration , chemistry , membrane potential , biochemistry , respiratory chain , biophysics , biology , botany , anatomy , cartilage

Simultaneous evaluation of two mitochondrial bioenergetics parameters, respiration rates and mitochondrial membrane potential (mtMP) can be useful to determine the mitochondrial dysfunction under various pathological conditions including neurodegenerative diseases and diabetes.

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