Net activity of phospholipase A2 in brain and the lack of stimulation of the phospholipase A2-acylation stem | Zendy

C. E. Rowe | Zendy

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Net activity of phospholipase A2 in brain and the lack of stimulation of the phospholipase A2-acylation stem

Author(s) -

C. E. Rowe

Publication year - 1977

Publication title -

biochemical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.706

H-Index - 265

eISSN - 1470-8728

pISSN - 0264-6021

DOI - 10.1042/bj1640287

Subject(s) - phospholipase a2 , stimulation , phosphatidylcholine , acylation , phospholipase , hydrolysis , guinea pig , chemistry , phospholipase c , phospholipase a , cerebral cortex , biochemistry , membrane , phospholipid , enzyme , biology , endocrinology , catalysis

Certain observations reported previously from this laboratory have not proved reproducible. These are (1) the relatively rapid hydrolysis of added phosphatidylcholine by phospholipase A2 of tissue from the cerebral cortex of the guinea pig and (2) the stimulation by 10 micron-noradrenaline and by 1.0nM-cyclic AMP of the phospholipase A2-acylation system of isolated synaptic membranes.

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