To code or not to code? That is the question for RNA in timekeeping
Author(s) -
Rebecca Mosig,
Shihoko Kojima
Publication year - 2020
Publication title -
the biochemist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 7
eISSN - 1740-1194
pISSN - 0954-982X
DOI - 10.1042/bio04202005
Subject(s) - genetic code , encode , dna , computational biology , rna , biology , code (set theory) , coding (social sciences) , source code , genetics , gene , computer science , sociology , programming language , social science , set (abstract data type)
Elementary cellular biology teaches that proteins are the main actors within cells. In addition, the DNA carries genetic information and the mRNA serves as the go-between molecule to create protein using the genetic code from the DNA. Recent advances in sequencing technologies have revealed that a large portion of our DNA is transcribed even though it does not appear to encode proteins. Further studies have shown that many of these non-coding RNAs (ncRNAs) serve regulatory functions within cells. Here, we examine the role of such molecules in the regulation of the circadian clock system as illustration of the wider ways in which ncRNAs can influence cellular processes.
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