Seminal reactive oxygen species, a novel biochemical assay for testing male fertility?

Infertility is defined as a failure to achieve a positive pregnancy test over 12 months of regular unprotected sex. It is a devastating condition affecting 15% of couples and is socially marginalizing. Despite significant focus on the female, nearly half of cases are in fact due to poor sperm function in the male partner. It is therefore surprising that despite the existence of numerous diagnostic tools and management options currently available for female infertility, very few exist for their male counterparts. So, what can we do to diagnose men with impaired fertility promptly and direct couples to effective management strategies?